Clinical resource

Brain adult glioma CNS WHO grade 3-4 astrocytoma or grade 4 glioblastoma EBRT short-course with or without chemotherapy (eviQ ID 410)

eviQ, Cancer Institute NSW

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DoseLab summary

Endorsed eviQ protocol for short-course radiotherapy of grade 3–4 astrocytoma and glioblastoma in older or less fit patients: 40.05 Gy in 15 fractions, 34 Gy in 10 fractions or 25 Gy in 5 fractions, with or without chemotherapy. Its organ table keeps the brainstem, optic structures, retina and cord below the prescription dose and gives a lens limit. Its review was due 30 June 2026.

Why this is useful

The short-course glioma schedules and the simple organ limits a protocol uses for them.

Reference details

Title
Brain adult glioma CNS WHO grade 3-4 astrocytoma or grade 4 glioblastoma EBRT short-course with or without chemotherapy (eviQ ID 410)
Authors / organization
eviQ, Cancer Institute NSW
Publication / protocol
eviQ Radiation Oncology protocol 410
Version
v.5 — last reviewed 28 March 2024; review due 30 June 2026
Year
2024
DOI
Pending verification
Disease sites
CNS / Brain
Topics
Glioma, Glioblastoma, Hypofractionation, Dose Constraints, Protocols
Fractionation context
40.05 Gy / 15 fx, 34 Gy / 10 fx or 25 Gy / 5 fx
Last reviewed by DoseLab
2026-09-25

Cited on DoseLab