Landmark trial

Sustained Preservation of Cognition and Prevention of Patient-Reported Symptoms With Hippocampal Avoidance During Whole-Brain Radiation Therapy for Brain Metastases: Final Results of NRG Oncology CC001

Gondi V, Deshmukh S, Brown PD, et al. · NRG Oncology

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DoseLab summary

Final results of NRG CC001 with more than a year of median follow-up: sustained preservation of cognition and fewer patient-reported neurologic symptoms with hippocampal avoidance. Citation checked against Crossref.

Why this is useful

Longer follow-up confirming the cognitive benefit of hippocampal avoidance.

Reference details

Title
Sustained Preservation of Cognition and Prevention of Patient-Reported Symptoms With Hippocampal Avoidance During Whole-Brain Radiation Therapy for Brain Metastases: Final Results of NRG Oncology CC001
Authors / organization
Gondi V, Deshmukh S, Brown PD, et al. · NRG Oncology
Publication / protocol
Int J Radiat Oncol Biol Phys. 2023;117(3):571–580
Version
Pending verification
Year
2023
DOI
10.1016/j.ijrobp.2023.04.030
Disease sites
CNS / Brain
Topics
Whole brain, Hippocampal avoidance, Brain metastases, Landmark trial
Fractionation context
30 Gy / 10 fx
Last reviewed by DoseLab
Pending verification

Cited on DoseLab