Landmark trial
Patient-Reported Toxicity During Pelvic Intensity-Modulated Radiation Therapy: NRG Oncology–RTOG 1203
Klopp AH, Yeung AR, Deshmukh S, et al. · NRG Oncology
DoseLab summary
NRG Oncology/RTOG 1203 (TIME-C) randomized women receiving post-operative pelvic radiation for endometrial or cervical cancer to IMRT or standard 4-field radiotherapy. IMRT reduced patient-reported bowel and urinary toxicity during treatment. Citation checked against Europe PMC.
Why this is useful
The randomized evidence for IMRT over 4-field pelvic radiation after hysterectomy.
Reference details
- Title
- Patient-Reported Toxicity During Pelvic Intensity-Modulated Radiation Therapy: NRG Oncology–RTOG 1203
- Authors / organization
- Klopp AH, Yeung AR, Deshmukh S, et al. · NRG Oncology
- Publication / protocol
- J Clin Oncol. 2018;36(24):2538–2544
- Version
- Pending verification
- Year
- 2018
- DOI
- 10.1200/JCO.2017.77.4273
- Disease sites
- GYN
- Topics
- Endometrium, Cervix, Post-operative, IMRT, RTOG, NRG
- Fractionation context
- Pending verification
- Last reviewed by DoseLab
- Pending verification