Clinical resource

NRG Oncology Protocol Development Template for Radiation Therapy — Gynecological Cancer: Endometrial Cancer (post-operative treatment after hysterectomy)

Lee YC, Kim H, Tsai P, Liang X, Padgett K, Portelance L · NRG Oncology Medical Physics Subcommittee / Radiation Oncology Committee

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DoseLab summary

The NRG Oncology template for the radiation section of a post-operative endometrial cancer trial. It covers supine or prone setup, vaginal apex markers, full- and empty-bladder scans fused to build the vaginal internal target volume, nodal CTV guidance, standard structure names, example prescriptions (45 or 50.4 Gy), example vaginal cuff brachytherapy schedules alone or as a boost, and per-protocol and variation-acceptable organ goals. For cuff brachytherapy it asks for dose points along the cylinder and verification of the dome position rather than volumetric organ limits. Its values are examples meant to be edited for each trial.

Why this is useful

How an NRG trial would write post-operative pelvic radiation for endometrial cancer, including the vaginal ITV, organ goals and vaginal cuff brachytherapy schedules.

Reference details

Title
NRG Oncology Protocol Development Template for Radiation Therapy — Gynecological Cancer: Endometrial Cancer (post-operative treatment after hysterectomy)
Authors / organization
Lee YC, Kim H, Tsai P, Liang X, Padgett K, Portelance L · NRG Oncology Medical Physics Subcommittee / Radiation Oncology Committee
Publication / protocol
NRG Oncology protocol template
Version
Version 1, May 2024
Year
2024
DOI
Pending verification
Disease sites
GYN
Topics
Endometrium, Post-operative, NRG, Protocols, Brachytherapy, Vaginal cuff, Image registration, Simulation, Structure naming, Dose Constraints
Fractionation context
45 Gy / 25 fx or 50.4 Gy / 28 fx; vaginal cuff HDR alone or as a boost
Last reviewed by DoseLab
2026-09-30

Cited on DoseLab