NRG Oncology Protocol Development Template for Radiation Therapy — Liver: SBRT

The template NRG Oncology gives investigators for the radiation therapy section of a liver SBRT trial, based on NRG GI-003. It strongly recommends implanted fiducials, allows several motion-management techniques, and describes the multiphase contrast CT used for hepatocellular carcinoma: non-contrast, arterial phase (hypervascular tumor), portal venous phase (vascular thrombus) and delayed phase (washout). Contrast-enhanced MRI is recommended when contrast CT can't be done.

Explains the multiphase contrast CT used to see hepatocellular carcinoma — arterial, portal venous and delayed phases — and when MRI is used instead.