Review article

A Story of Hypofractionation and the Table on the Wall

Timmerman R · UT Southwestern Medical Center

View Source Source Verified

DoseLab summary

An editorial history of the UT Southwestern SABR constraint tables — often called the “Timmerman tables” — covering how they were developed and revised, and their relationship to AAPM TG-101 and NRG/RTOG protocols. Tables 2–11 separate serial tissues (listed with a volume, a volume max and a max point dose) from parallel tissues (listed with a critical volume and a critical-volume dose max). In Tables 2–7 a footnote defines “point” as ≤0.035 cm³; Tables 8–11 add a contouring-instructions column for each structure.

Why this is useful

One article that holds constraint tables for ten fraction counts, from single-fraction SABR to conventional 30-fraction treatment — plus the history of why versions of these tables differ.

Reference details

Title
A Story of Hypofractionation and the Table on the Wall
Authors / organization
Timmerman R · UT Southwestern Medical Center
Publication / protocol
Int J Radiat Oncol Biol Phys. 2022;112(1):4–21
Version
Pending verification
Year
2022
DOI
10.1016/j.ijrobp.2021.09.027
Disease sites
Lung, Other, CNS / Brain
Topics
SBRT, Dose Constraints, Hypofractionation, Serial vs Parallel
Fractionation context
1, 2, 3, 4, 5, 8, 10, 15, 20 and 30 fractions (Tables 2–11)
Last reviewed by DoseLab
2026-09-22

Cited on DoseLab