The alfa and beta of tumours: a review of parameters of the linear-quadratic model, derived from clinical radiotherapy studies

Systematic review of 64 clinical studies reporting α, β and α/β for human tumors. It found large heterogeneity within and between studies; estimates for prostate and breast tumors generally indicated high fractionation sensitivity, those for head & neck, cervix, bladder and liver tumors low sensitivity, and others were mixed. It notes that whether the LQ model holds at large fraction sizes is debated, and recommends choosing parameters by site, histology and model and exploring a range of values. Full text read in Europe PMC (PMC5956964).

Why a single α/β of 10 Gy does not fit every tumor — a systematic review of published α/β values by tumor site and histology.