Head & Neck · Organ at risk

Submandibular Glands

Educational Summary

Dose constraints

Head & Neck Planning Essentials

ScheduleConstraintSource
Conventional fractionation
70 Gy / 35 fx definitive · 60–66 Gy / 30–33 fx post-op
Mean ≤39 GyMurdoch-Kinch 2008

Quoted from eviQ 5049, checked 2026-09-24. Full table with references →

Anatomy

Salivary glands beneath the floor of the mouth, in the submandibular triangle along the inner surface of the mandible — within neck level Ib.

Function in the body

Salivary glands under the floor of the mouth. They produce much of the saliva that keeps the mouth moist between meals.

Why it matters

The submandibular glands produce most of the resting (unstimulated) saliva that keeps the mouth moist between meals and overnight. They can be spared only when level Ib is not in the target, which depends on the subsite and nodal stage.

How to contour

Brouwer 2015 gives these boundaries (Table 1):

  • Top: the medial pterygoid and mylohyoid muscles.
  • Bottom: fatty tissue.
  • Front: the outer surface of the mylohyoid and hyoglossus muscles.
  • Back: the parapharyngeal space and the sternocleidomastoid muscle.
  • Outside: the inner surfaces of the medial pterygoid muscle and the mandible, and the platysma.
  • Inside: the outer surfaces of the mylohyoid and hyoglossus muscles, the superior and middle pharyngeal constrictors, and the anterior belly of the digastric muscle.

Further reading

  • Murdoch-Kinch 2008 — Dose-effect relationships for the submandibular salivary glands and implications for their sparing by intensity modulated radiotherapy Source

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